Virginia is the only Southern state with Democratic US Senators, Warner and Kaine. The remainder of the South is now solidly Republican for the first time ever.
The transformation has taken place most recently in Louisiana, West Virginia, and North Carolina, with Democratic losses in the 2012 election. It’s hard to imagine Louisiana and West Virginia electing Democratic senators anytime soon.
Last Southern Democrat, Mary Landrieu, Loses Senate Seat (The Atlantic)